THCV - What The Lab Reports Say

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We have spoken about the new and exciting cannabinoid on the block, otherwise known as THCV, or ‘diet weed’. Delta 9 tetrahydrocannabivarin (THCV)  is a cannabis-derived compound with unique properties that set it apart from the more common cannabinoids, which we spoke about in our previous article here.


As we mentioned in the last article,  although THCV shares a similar molecular structure with the most known THC, this cannabis compound is not intoxicating and has no psychoactive effects.  The parent molecule for THCV and its acidic form tetrahydrocannabivarin acid (THCVA) is cannabigerovarinic acid (CBGVA), which is formed when geranyl pyrophosphate reacts with divarinolic acid. Similar to CBN, THCV is unusual as it is only intoxicating in high doses. 


The difference between THCV and THC


THCV is a naturally occurring analog of THC. In contrast to THC, which is psychoactive and an agonist at the CB1 and CB2 receptors, THCV is a non-psychoactive, neutral CB1 antagonist / reverse agonist and may act as an agonist or antagonist at the CB2 receptors depending on its dose. Cannabis compounds, like THC and CBD, can bind to both receptors to signal that the endocannabinoid system needs to take action. 


THCV acts in the same way as other cannabis compounds. But while most people associate THC with increasing appetite, THCV has the opposite effect as it blocks the CB1 receptor, which is well known to stimulate appetite. 


THCV has gained the nickname of the “race car” of cannabinoids, as high doses reportedly give users a short-lasting but very energetic high.


How Can You Find THCV?


Unlike cannabinoids such as CBN and CBC, there are relatively high levels of THCV in a wide variety of marijuana strains. There are only a limited number of plants out on the market that produce viable quantities of this compound, and they’ve generally been hard to grow, low-yielding plants. The supply chain is not strong, it’s a rare cannabinoid. The market is expanding and people are isolating THCV from plants and infusing it into different manufactured products, like edibles and cannabis drinks


Fortunately, States that have legalized in cannabis require testing for potency and contaminants in cannabis, and lab-testing cannabis is quickly becoming an important part of the industry. The tests for pesticides, mold, contamination, etc. don’t require any new or special analytical techniques and are part of standard practice for other agricultural products as well. 


Lab reports and testing of THCV


Unlike HHC, THCO and other synthetic cannabinoids - THCV is extremely clear of pesticides, heavy metals and contains high cannabinoid and terpene levels. In the lab report below you can clearly see the pesticide testing.




In another two lab reports, it clearly shows the high THCV level as seen below;



Similarly, both reports show a clear pass for pesticides;



cannabis has long been grown with the help of large quantities of pesticides, including some intended only for ornamental plants and many that are associated with cancer or other serious health effects. But cannabis yields are valuable, and losing a crop to mites or mold means forfeiting many thousands of dollars. Growing plants indoors to escape detection often increases the risk that insect infestations and harmful microbes will spread quickly. For illicit growers with little knowledge of other methods and no regulatory oversight, it is easier and cheaper just to spray. That’s why these reports are incredibly important to the safety of the end product.


Cannabis consumed in combustive form represents the greatest danger to human health, as analysis of heavy metals in the smoke of cannabis revealed the presence of selenium, mercury, cadmium, lead, chromium, nickel and arsenic. Heavy metals are a risk posed to any process requiring extraction or isolation, such as THCV,


The upside is, however, that based on the lab reports below - THCV is fairly clear of heavy metals after the processes that it undergoes. In this instance, the product is D8-THCV Isolate.



These passes carry over to the residual solvents too, all coming through with a pass status - meaning that the end product is clear from impurities from the solvent remain in the extracted material. In some cases, these impurities can be toxic, which is why residual solvent analysis is a critical element of cannabis testing, especially for synthetic cannabinoids that we have covered previously.



As you can see from the report, which is consistent amongst the other reports; the terpene value in THCV high cannabinoids are incredibly high, with the total terpenes being 2.979%. 


Aside from cannabinoids, terpenes are elements present in the cannabis plant which play a significant part in producing the effects associated with cannabis. These organic compounds produce aromatic and flavour diversity. They function in a similar manner to cannabinoids in that they bind to receptors in the brain and produce different effects.


These aspects are all important for the end product, and more importantly for a product high in THCV like the ones that we offer in our latest strains. The safety of a product should take priority, but so should the terpene and cannabinoid levels. 

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