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Everything you need to know about CBDV

With countries worldwide slowly legalizing cannabis, research is finally growing and we’re constantly finding out more about the 120+ cannabinoids in the marijuana plant, namely CBDV, otherwise known as Cannabidivarin. 

People are looking beyond conventional THC or CBD and seeking out new cannabinoids like this one, and in this article, we will explain why CBDV is worth looking into. The laws have limited public access and therapeutic research on non-psychoactive cannabinoids. Fortunately, we’re discovering more and more cannabinoids that are non-psychoactive and still have the healing properties of cannabis.

So, what is CBDV?

Cannabidivarin (CBDV) is a Varin cannabinoid first reported in a benzene extract from a Thai cannabis variety referred to as “Meao” in 1977, and identified for the first time in 1969 Vollner et al. CBDV is a homolog of CBD and is a non-psychoactive cannabinoid. As you can see below, The slight difference here is the propyl chain that CBDV carries. 

 

Like CBD, cannabidivarin has 7 double bond isomers and 30 stereoisomers. There is a side-chain shortened by two methylene bridges. The biggest difference between CBD and CBDV is their concentrations in the cannabis plant. You can find trace amounts of CBDV in high-quality full-spectrum and broad-spectrum extracts that help to produce the entourage effect.

Varin cannabinoids (technically called varinolic cannabinoids) are a subfamily of cannabinoids that feature three carbons on their alkyl side chains. The most well-known examples are THCV, CBDV, CBGV, and CBCV. There are also acid forms of THCVA, CBDVA, CBGVA, and CBCVA.

CBDV exists in very small quantities. Recently, several African landrace strains (which are genetically pure and unimpacted by experimentation) of Cannabis indica were found to have CBDV and the related THCV in concentrations closer to 4%. There are also plant breeders creating high CBDV and THCV strains of hemp and marijuana — but the current record still sits below 7% CBDV. 

What are the medicinal effects?

Epilepsy

Due to the rise in popularity of CBDV, researchers are trying to discover its medical benefits. In 2014, GW Pharmaceuticals finished a Phase 1 clinical trial of its CBDV test product (known as GWP42006). The clinical trial explored the use of CBDV as an anti-epileptic drug. The company continues to research CBDV heavily. You won’t feel a psychoactive ‘high’ from CBDV. Instead, you can expect it similar effects to CBD. The lack of a ‘high’ means we can use CBDV similarly, which is still being researched.

GW were set to enter Phase III trials in late 2019 but had to terminate the study because of the pandemic. They’re currently recruiting for a new trial, and the CEO Justin Gover made the following statement;

“CBDV represents an additional product pipeline opportunity as a next-generation epilepsy therapy.”

This study follows the completion of a Phase 1 trial in 66 healthy subjects in 2014. In this trial, CBDV was well tolerated even at the highest tested dose and no significant side effects were observed. Most importantly, following this trial, There were no serious or severe adverse events, nor any withdrawals due to adverse events.

Rett Syndrome

As you may know, Rett syndrome (RTT) is a rare neurodevelopmental disorder, characterized by severe behavioral and physiological symptoms with no cure available to date. A study was done on mice with CBDV being administered for 14 days. The study restored compromised general health status of the mice, the sociability, and the brain weight in RTT. While more studies are required, this shows great promise for the medical use of CBDV.

Autism

Some of the most interesting recent research into CBDV has been around the subject of autism. This condition, which affects more children and adults every year, is still being researched to find effective medications. The use of CBDV for autism has rapidly gained popularity over the last two years.

The study suggests that CBDV targets subcortical excitatory glutamate systems both in autistic and neurotypical adults. This study compared the effects of CBDV in neurodiverse patients and neurotypical patients. They noted a higher degree of difference in ASD patients with elevated glutamate. Very little benefit was reported on those with normal glutamate levels.

Some studies have even shown that people diagnosed with autism spectrum disorder (ASD) have below-average anandamide levels in the brain, one of the body’s endocannabinoids. 

Pain

In this study, patients underwent two successive treatment phases (4 weeks each) and were treated with CBDV. While the study wasn’t necessarily conclusive, it did explore the potential utility of CBDV for neuropathic pain. 

While CBDV research is increasing, so far there are no guarantees that cures or applications have been or will be found. The existing CBDV studies and research papers indicate grounds for medical optimism that previously may not have existed. With the growing interest in the industry, there’s endless potential. Fortunately, there should not be severe restrictions on CBDV, considering its lack of psycho-activity. 

CBDV and the endocannabinoid system:

CBDV interacts with the endocannabinoid system (ECS) the same way as CBD. However, it’s thought to have about 25% of CBD potency. CBDV does not stimulate the ECS as CBD and THC do; it has a modulating action instead. According to the British Pharmacological Society;

“CBDV and all the acids inhibited DAGLα.”

DAGLα is an enzyme responsible for the synthesis of the endocannabinoid 2-AG.

Is CBDV Legal? 

CBDV is legal in the United States, as long as it is produced from Hemp rather than marijuana. This is because CBDV derived from marijuana is illegal on a federal level and is considered a schedule 1 drug by the Drug Enforcement Agency (DEA). Some states have legalized marijuana for medicinal or recreational use. The states that have legalized marijuana have also legalized its derivatives, including CBDV. 

CBDV derived from hemp containing no more than 0.3 percent THC is considered legal on a federal level due to the 2018 Farm Bill. This Bill gave states the power to further regulate hemp products, which some states have by restricting any traces of THC. Although hemp-derived CBDV is difficult to find, it’s legal in all states as long as it abides by the state THC regulations. 

What is the difference between CBDV and CBD?

As previously mentioned, the molecular structures between CBD and CBDV are different, which impacts their chemical responses. Furthermore, CBDV can be used to develop THCV (tetrahydrocannabivarin) when it’s exposed to an acidic environment. CBD doesn’t have this same ability to transform into THC. When dealing with CBDV vs CBD, both cannabinoids share huge similarities that could be a massive hit in the medical industry because of the therapeutic effects offered. Above all, CBD and CBDV both interact with the endocannabinoid system, but CBDV binds with the cannabinoid receptors and CBD simply interacts or blocks the receptors.

Based on all the information provided, it’s clear why Cannabidivarin might be the next significant cannabinoid the world will witness, and we can only hope that research increases to increase the use of CBDV globally.

January 11, 2022
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Everything you need to know about CBDV

With countries worldwide slowly legalizing cannabis, research is finally growing and we’re constantly finding out more about the 120+ cannabinoids in the marijuana plant, namely CBDV, otherwise known as Cannabidivarin.

People are looking beyond conventional THC or CBD and seeking out new cannabinoids like this one, and in this article, we will explain why CBDV is worth looking into. The laws have limited public access and therapeutic research on non-psychoactive cannabinoids. Fortunately, we’re discovering more and more cannabinoids that are non-psychoactive and still have the healing properties of cannabis.

So, what is CBDV?

Cannabidivarin (CBDV) is a Varin cannabinoid first reported in a benzene extract from a Thai cannabis variety referred to as “Meao” in 1977, and identified for the first time in 1969 Vollner et al. CBDV is a homolog of CBD and is a non-psychoactive cannabinoid. As you can see below, The slight difference here is the propyl chain that CBDV carries.

What is CBDV?

Like CBD, cannabidivarin has 7 double bond isomers and 30 stereoisomers. There is a side-chain shortened by two methylene bridges. The biggest difference between CBD and CBDV is their concentrations in the cannabis plant. You can find trace amounts of CBDV in high-quality full-spectrum and broad-spectrum extracts that help to produce the entourage effect.

Varin cannabinoids (technically called varinolic cannabinoids) are a subfamily of cannabinoids that feature three carbons on their alkyl side chains. The most well-known examples are THCV, CBDV, CBGV, and CBCV. There are also acid forms of THCVA, CBDVA, CBGVA, and CBCVA.

CBDV exists in very small quantities. Recently, several African landrace strains (which are genetically pure and unimpacted by experimentation) of Cannabis indica were found to have CBDV and the related THCV in concentrations closer to 4%. There are also plant breeders creating high CBDV and THCV strains of hemp and marijuana — but the current record still sits below 7% CBDV.

What are the medicinal effects?

Epilepsy

Due to the rise in popularity of CBDV, researchers are trying to discover its medical benefits. In 2014, GW Pharmaceuticals finished a Phase 1 clinical trial of its CBDV test product (known as GWP42006). The clinical trial explored the use of CBDV as an anti-epileptic drug. The company continues to research CBDV heavily. You won’t feel a psychoactive ‘high’ from CBDV. Instead, you can expect it similar effects to CBD. The lack of a ‘high’ means we can use CBDV similarly, which is still being researched.

GW were set to enter Phase III trials in late 2019 but had to terminate the study because of the pandemic. They’re currently recruiting for a new trial, and the CEO Justin Gover made the following statement;

“CBDV represents an additional product pipeline opportunity as a next-generation epilepsy therapy.”

This study follows the completion of a Phase 1 trial in 66 healthy subjects in 2014. In this trial, CBDV was well tolerated even at the highest tested dose and no significant side effects were observed. Most importantly, following this trial, There were no serious or severe adverse events, nor any withdrawals due to adverse events.

Rett Syndrome

As you may know, Rett syndrome (RTT) is a rare neurodevelopmental disorder, characterized by severe behavioral and physiological symptoms with no cure available to date. A study was done on mice with CBDV being administered for 14 days. The study restored compromised general health status of the mice, the sociability, and the brain weight in RTT. While more studies are required, this shows great promise for the medical use of CBDV.

Autism

Some of the most interesting recent research into CBDV has been around the subject of autism. This condition, which affects more children and adults every year, is still being researched to find effective medications. The use of CBDV for autism has rapidly gained popularity over the last two years.

The study suggests that CBDV targets subcortical excitatory glutamate systems both in autistic and neurotypical adults. This study compared the effects of CBDV in neurodiverse patients and neurotypical patients. They noted a higher degree of difference in ASD patients with elevated glutamate. Very little benefit was reported on those with normal glutamate levels.

Some studies have even shown that people diagnosed with autism spectrum disorder (ASD) have below-average anandamide levels in the brain, one of the body’s endocannabinoids.

Pain

In this study, patients underwent two successive treatment phases (4 weeks each) and were treated with CBDV. While the study wasn’t necessarily conclusive, it did explore the potential utility of CBDV for neuropathic pain.

While CBDV research is increasing, so far there are no guarantees that cures or applications have been or will be found. The existing CBDV studies and research papers indicate grounds for medical optimism that previously may not have existed. With the growing interest in the industry, there’s endless potential. Fortunately, there should not be severe restrictions on CBDV, considering its lack of psycho-activity.

CBDV and the endocannabinoid system:

CBDV interacts with the endocannabinoid system (ECS) the same way as CBD. However, it’s thought to have about 25% of CBD potency. CBDV does not stimulate the ECS as CBD and THC do; it has a modulating action instead. According to the British Pharmacological Society;

“CBDV and all the acids inhibited DAGLα.”

DAGLα is an enzyme responsible for the synthesis of the endocannabinoid 2-AG.

Is CBDV Legal?

CBDV is legal in the United States, as long as it is produced from Hemp rather than marijuana. This is because CBDV derived from marijuana is illegal on a federal level and is considered a schedule 1 drug by the Drug Enforcement Agency (DEA). Some states have legalized marijuana for medicinal or recreational use. The states that have legalized marijuana have also legalized its derivatives, including CBDV.

CBDV derived from hemp containing no more than 0.3 percent THC is considered legal on a federal level due to the 2018 Farm Bill. This Bill gave states the power to further regulate hemp products, which some states have by restricting any traces of THC. Although hemp-derived CBDV is difficult to find, it’s legal in all states as long as it abides by the state THC regulations.

What is the difference between CBDV and CBD?

As previously mentioned, the molecular structures between CBD and CBDV are different, which impacts their chemical responses. Furthermore, CBDV can be used to develop THCV (tetrahydrocannabivarin) when it’s exposed to an acidic environment. CBD doesn’t have this same ability to transform into THC. When dealing with CBDV vs CBD, both cannabinoids share huge similarities that could be a massive hit in the medical industry because of the therapeutic effects offered. Above all, CBD and CBDV both interact with the endocannabinoid system, but CBDV binds with the cannabinoid receptors and CBD simply interacts or blocks the receptors.

Based on all the information provided, it’s clear why Cannabidivarin might be the next significant cannabinoid the world will witness, and we can only hope that research increases to increase the use of CBDV globally.

January 11, 2022
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Vape Legislation changes in Illinois & Oregon

It’s a new year, and with the new year comes new laws that are to take effect, and for the cannabis and vape industry - these laws may not be as promising for the future of the industry. We’ve seen several states take a stance against vaping specifically, and added to the list are Illinois and Oregon. This article will cover everything you need to know about what this means for the vape community in these states moving forward.

Illinois

As of January 1st, 2022, the state of Illinois has passed a new bill, namely Illinois Senate Bill 00512 - The “Preventing Youth Vaping Act” which was sponsored by Sen. Julie Morrison and Rep. Bob Morgan. This bill is as the name suggests; a bill that creates additional restrictions and regulations on e-cigarettes, aiming to prevent vaping by children. So, what does this act mean for Illinois?

First of all, the law defines an e-cigarette as;

  • A device using a battery or other mechanism to heat a solution, resulting in vapor for inhalation.
  • Any container of a substance that is intended to be used in the device or used to refill the device.
  • Any substance that is intended for use in the device.

According to the Illinois attorney general, the act is intended to do the following;

“Address the epidemic levels of youth e-cigarette usage by prohibiting companies from marketing products to minors.”

The state has clearly stated its interest and belief in encouraging the youth to live vape-free. While vaping is a controversial topic in regards to health, the state has a strong stance in stepping towards keeping these products out of the hands of anyone younger than 21 years old. This bill, however, also poses a challenge to the industry by limiting companies from directing their advertising and marketing.

While most people may stand by the age-restricted purposes of this bill, this legislative change poses nuanced difficulties to companies that offer these products and results in fines of up to $25,000 as well as a 1-3 year prison sentence if found guilty. The bill complicates marketing these products by stating the following rules:

  1. Companies can not market vape products as modified risk tobacco products
  2. Companies can not market a vape product as providing smoking cessation benefits unless approved by the FDA.
  3. Companies can not market vape products in a way that appeals to or encourages any person under the age of 21 to use them.

As online tobacco and e-cigarette sales continue to grow, the new law and restrictions as listed above seek to prevent minors from purchasing e-cigarettes by requiring online retailers to take steps to ensure that purchasers are at least 21 years old. The state goes as far as urging the FDA to ban flavored tobacco products and to strengthen e-cigarette guidance by prioritizing enforcement actions against flavored e-cigarettes.

The only exception currently stands for the following;

“Electronic cigarettes first sold prior to August 8, 2016 and for which a premarket tobacco product application was submitted to the U.S. Food and Drug Administration by September 9, 2020”

e-cigarettes that utilize synthetic (tobacco-free) nicotine or CBD-containing e-cigarettes, for example, that arguably are not tobacco products under federal law, would not be considered adulterated in Illinois for not having authorized PMTAs.

Oregon

As of January 1st, 2022, the state of Oregon passed House Bill 2261 which prohibits remote sales of inhalant delivery systems. This new legislation prevents any businesses involved in selling vape products from shipping or mailing any products that may have been purchased online or by other distant means. This means that the only sales permitted are in-person sales.

These restrictions do not, however, apply to freight forwarders or motor carriers. Apart from that exception, no retailers or businesses may sell smokable tobacco products unless the purchase was made face-to-face.

‘Inhalation delivery systems’ refers to anything that is one of the following;

“A device that can be used to deliver nicotine in the form of a vapor or aerosol to a person inhaling from the device; or a component of a device described in this paragraph or a substance in any form sold for the purpose of being vaporized or aerosolized by a device described in this paragraph, whether the component or substance is sold separately or is not sold separately.”

According to that description, the following products fall into the Oregon HB 2261 Shipment ban:

  • Bottled e-liquid (with or without nicotine)
  • Closed-system ENDS (e.g. pod/cartridge or disposables) pre-filled with non-nicotine and nicotine-containing e-liquids
  • Open-system devices
  • Open-system/Open-tank ENDS device

This means that the legislation appears to restrict the DTC sale of most types of vapor products.

The implementation of this bill was put forward due to the FDA reporting that 3.6 million middle and high school students were current users of e-cigarettes In 2020. While the FDA finalized a rule in 2016 that included ENDS in the definition of a tobacco product, the majority of regulation of these products is left to the states. Supposedly, despite the current regulations that were passed in 2017 - the state insisted that the regulations still make it relatively easy for minors to obtain products online.

A device is considered adulterated if:

  1. It consists of any poisonous, deleterious or filthy substance that may render injuries to health.
  2. It is held or packaged in containers composed of any poisonous or deleterious substance.

Considering these new legislations, it is clear that further restrictions are being imposed on the states around the U.S. and pose challenges to the vapor industry. While these new bills are proposed to provide a safer environment for minors, it should be asked whether this is a step forward or a step backward in the industry.

January 5, 2022
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A Guide to Curing and Drying

As many of you know, curing and drying are processes that can significantly impact the taste and general quality of your cannabis crop. Properly drying and curing your fresh cannabis stash is paramount to prevent harsh smoke and prevent mold contamination from taking place.

Harvesting your cannabis is only half the work. Post harvest operations are arguably just as important as pre-harvest. Many believe that curing and drying are the same things, which they aren’t. Black Tie CBD has been asked why we haven’t released our 2021 strains, and the answer is simple; we believe in a low and slow curing process that ensures quality to the end product that we offer you.

Below, we’ll share our answers to some frequently asked questions on the drying and curing processes, so you can maximize the flavor and potency of your stash - as well as better understand how post-harvest processes are done correctly.

The importance of drying cannabis

Freshly harvested cannabis buds contain significant moisture, which needs to be dealt with before smoking. Essentially, drying also converts THC from its non-psychoactive, crude, acidic form to its psychoactive neutral form.

Cannabis flowers are full of active components; The resin glands contain THC, CBD and other cannabinoids. The issue is that when your plants are recently harvested, they’re still quite green and most of the THC is inactive. Drying marijuana means reducing the water content of the buds to 10-15%, depending on the desired crispiness of the final product.

A dry shouldn’t be too quick or the outside of buds will appear dry but the insides won’t be, leaving chlorophyll within; too long, and buds could develop mold.

How do you dry cannabis?

The drying procedure usually depends on the trimming process that you use;

  • Dry trimming
  • If you’re trimming plants after they’ve been dried, then you’ll be able to hang them from a line or hanger. Hanging is preferable as it prevents buds from becoming misshapen. To test if the plants are ready for trimming, you can try bending a branch. If it bends, it needs more drying. If it snaps, it is ready for trimming and curing.
  • Wet trimming
  • If you trim the plants before drying, you’ll have smaller plant parts to dry and need to use a rack. You can check when buds are ready for curing by squeezing them. If they still feel wet or moist, they likely need more time before moving on to curing.

Dying cannabis involves focusing on:

  • The drying method used.
  • Temperature.
  • Moisture levels.

What are the drying methods?

Hang Drying Cannabis

Hang drying is a cost-effective solution for cannabis cultivators with a limited budget and involves exposing your cannabis to the open air. To hang-dry your cannabis, your branches are hung upside down from an elevated position and dried. You must regularly monitor the temperature and airflow of the room for the best results.

Choosing a cool, dark place to dry your buds is essential. Ensure that your flowers are spaced adequately for airflow to carry moisture particles away without attracting mold. Hang-drying is great, but requires a lot of environmentally controlled space.

This process usually takes anywhere from 1-2 weeks.

Using a drying rack

When preparing cannabis for commercial purposes, trimming machines are usually used, so this method is ideal. A drying rack is great for keeping the yield organized, and there is far lower risk of contamination or mold. While this option is more pricey, it is the ideal piece of equipment when it comes to drying weed correctly. Using a drying rack with a large surface area for the buds allows for more airflow, meaning that the moisture is taken away in far less time.

Again, this is a process that takes upwards of 10 days. If the snapping sound of your bud is crispy and sharp, then you know that your weed has been dried properly.

While you may be looking for a faster drying process, If buds are dried too quickly, chlorophyll and other pigments, starch, and nitrates are trapped within plant tissue, making it taste “green,” burn unevenly and taste bad. However, slowly dried buds taste sweet and smoke smooth. Taste and aroma improve when pigments break down. Slow even drying–where moisture content is the same throughout stems, foliage and buds– allows enough time for the pigments to degrade.

How to perfect the drying process:

As stated above, we focus on a slow drying process. We hang entire plants to dry; allowing the process to take place over time. We remove large leaves and stems (fan leaves) in the field as fresh leaves are easier to work with. The plants are then hung until they reach an ideal moisture content. At that point they buds are hand-trimmed and placed into curing.

Temperature:

We place importance on circulation and ventilation as this helps us control the heat and humidity of the room. The ideal air temperature is between 65 and 75°F (18-24°C), and humidity from 45-55%. Any temperatures lower may slow drying and increase the threat of harsh smoke, and any temperatures higher may cause the buds to mold.

Similarly, any lower than suggested humidity causes a speedy dry period, causing the retention of chlorophyll and giving the weed a terrible taste and odor.  The most important thing to note is that different climates are required for growing cannabis and drying it.

Hanging:

Due to the quantity of cannabis that we dry, we use a large space for drying. It is ideal to cut the plants at the base and remove the large leaves - then hang them on the drying lines in the drying facility. Branches should be cut from 12-40 inches, with each branch manicured and hung.

Manicured branches should be hung to dry for a few days before being bucked from the stem and placed on drying screens to allow the bulk of the moisture to dissipate. Once it is all on screens, the buds should be turned daily to ensure even drying. It is also adequate for manicured buds to be placed in boxes to dry, but the drying pace is slower due to the limited airflow.

Drying time:

Drying can take between five to seven days depending on temperature, humidity and bud density. The larger, denser buds can take around four days longer, so it’s important to check your buds to determine the proper moisture content. If you want to check the readiness, bend the stem and ensure that it snaps rather than folds; this generally indicates that it is ready to cure.

The importance of curing cannabis:

The curing process is possibly the most overlooked aspect of producing cannabis. During curing, moisture continues to draw from the center of the bud toward the outside.

Curing your bud is similar to the aging process of products like wine and cheese. Instead of a fermentation process, the main focus is on humidity with curing weed. Because even-though most moisture has evaporated and left the cannabis during the drying of the plants, there’s still some moisture left in the weed. Any friction and rough handling of the buds will knock off valuable resin glands and diminish the cannabinoid content.

The first week of curing affects potency as it evenly removes moisture within the bud so virtually all the THC is psychoactive, which is what most people are after. Curing also allows buds to dry enough that mold does not grow when buds are stored. Well-cured buds have an even glow when burned and smoke smooth. It is essentially not enough to simply keep your weed in a jar and say that it’s been correctly cured.

The process of curing cannabis:

The first step to curing your cannabis is to cut the stems into lengths less than 30-45 cm and then place them into an airtight container, ideally with a rubber seal. Any Ziploc or plastic bags are not ideal - some growers say that plastic imparts an undesirable flavor on the buds and is not impervious to oxygen.

Once the buds are enclosed, a microclimate is created, and the buds get an even spread of moisture. Once the buds are enclosed, they should be stored in a cool, dry, and dark place. Check on your buds at least once per day for two weeks. Use a hygrometer to check relative moisture in the container during the curing process. If you don’t have a hygrometer handy, you can gently squeeze to feel if they are moister than before.

During this check-up, keep your jars open to allow for air exchange, and inspect each bud individually for signs of mold. If you find an infected bud, make sure to remove it from its jar immediately to avoid the fungus spreading. If buds are sticking together in clumps when you try to shake the container, it means they still have too much moisture and need to be dried further.

Ideal conditions for drying cannabis:

Humidity

You want to stabilize the relative humidity at around 45-55% when the buds are placed in an enclosed container. This is the correct environment to cure your cannabis buds to perfection.

Temperature

65-75

Light

None

If buds are too dry:

leave them in the container and let excess moisture escape out the top by opening the container for a few minutes every few hours before closing the lid again.

If buds are too moist:

If you live in a normal to dry climate, you may be able to get away with just leaving the top off the jars for 1-4 hours. If you live in a humid climate, you may have to take the buds out of the jars and lay them out until the outsides begin to feel dry again.

The curing process is most important during the first two weeks and can take over six months for the highest quality outcome. It’s clear that this process is incredibly long when done correctly, which is why we release our new strains later than most other companies. We place the utmost importance on a long process that ensures the highest quality outcome.

December 21, 2021
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Turning Trim Into Edibles

Cannabis trim is a common term used to describe the excess parts a cultivator must trim, or remove from their plants post-harvest in order to fully maximize a plant’s bloom and, in turn, get more desirable crystals.

Cannabis trim refers to two different types of leaves:

  • Sugar leaves are the small leaves that grow out of the buds: Heavily concentrated trichomes, so they’re better for various extractions. Some people do not trim the sugar leaves and just leave them on the buds. This has the advantage of making the harvest heavier and the buds more appealing. In some cases, the sugar leaves are also packed with large amounts of THC.
  • Fan leaves are the larger leaves that protrude from the branches: Fewer trichomes and therefore fewer cannabinoids and terpenes, making it less effective for psychoactive products. Since fan leaves contain far fewer trichomes, you won't get a good yield for rosin extract, but you can make edibles with it as we will discuss below.

Typically, removing trim helps remove some unnecessary parts of the plant, at least in terms of smoking. However, the trim should not be deemed useless.

Preparing the trimmings:

Preparing the trimmings is an important part of the process when making edibles. The first step is to gather the leaves and dry them in a well-ventilated area, then chop the dried cannabis leaves into pea-sized pieces. Lastly, remove the stems (Since stems don’t contain enough cannabinoids to affect the potency).

The next step is to decarboxylate. The process involves heating the cannabis to convert inactive THCA and CBDA to active THC and CBD. If you don't properly decarb your cannabis, the moisture from it can cause botulism bacteria to grow in your tinctures, butters or oils - making it an important process.

You’ll need the following equipment:

  • An oven
  • A baking sheet
  • Parchment paper
  • Cannabis trim
  1. Step 1: Preheat the oven to 235 degrees Fahrenheit (120 degrees Celsius). Place the parchment paper on the baking sheet and spread your marijuana, or hemp flower across it.
  2. Step 2: Bake for approximately 40 minutes
  3. Step 3: Remove and let cool. The process is now complete.

Making Edibles With Trim:

You can typically use trim just as you would cannabis flower, but there are a few differences to be aware of. Edibles are easy to make with trim, and just as tasty, although it's important to know that you may end up with a more green-colored and pungent tasting end product due to the high levels of chlorophyll.

THC is fat soluble, so you need to put the trim in some type of fat. The most common are oil, butter or milk. Let’s take a look at how you can make the various edibles;

Cannabis Butter (cannabutter):

Infusing butter with cannabis to make ‘cannabutter’ with trimmings is one of the most popular and simplest ways to make cannabis-infused edibles. It is the main ingredient for a wide range of marijuana edibles. Most homemade edibles start with cannabutter. Butter is an ideal host for infused cannabis. Its pliability makes it really versatile for carrying THC and other cannabinoids.

Here is an easy recipe for how to make cannabutter with trim (the sugar leaves removed from harvested plants). What you’ll need:

  • Cannabis trim
  • Water
  • Cookie sheet
  • Salted butter
  • Stirring spoon
  • Cooking pot
  • sharp knife

Step 1: After decarboxylating, chop up your trimmings, or use a kitchen blender.

Step 2: Melt your butter in the cooking pot and add water.

Step 3: Add the trim into the pot and let it simmer for about 4-8 hours, but you can let it simmer for longer if you are aiming for extreme potency.

Step 4. Add water as needed because it evaporates and the level in the pot lowers.

Step 5. Strain the mixture after the boiling is complete

Step 6. Place the butter into containers, let it cool and store it in the fridge

Once the process is complete, your cannabutter should look something like this;

Cannabis Butter

How To Dose Cannabutter

Dosing homemade edibles is a complex but necessary part of the process. Each batch varies, depending on your type of cannabis and cooking techniques. All you need to know is how much cannabis you used in your butter and its THCA percentage.

Here is the calculator as provided by ‘INSIDER’;

Dose Cannabutter

10 milligrams is the standard dose for edible companies. 10 milligrams will feel relaxing, a bit euphoric, sedative, and calming for most people. If you have never consumed cannabis before, start even lower at 5 milligrams and build from there.

What to make with cannabutter

  • Cannabutter fudge
  • Peanut butter cookies
  • Blondies
  • Cheesecake
  • Tarts

Cannabis-infused Coconut Oil:

Cannabis-infused coconut oil packs the potency without the animal fat for plant-based edibles. Nearly pure fat, coconut oil effortlessly binds to the cannabinoids in cannabis and has a higher smoke point than some other oils. Coconut oil is an accessible and versatile base for creating strong cannabis infusions, topicals, and medicinal edibles because of its high saturated fat content.

Not only is cannabis-infused coconut oil a great holder of potency, but it is also adaptable to different diets like ketogenic and vegan - all while tasting great. When you compare the coconut oil fat content with Olive oil, there is a difference of over 60% with coconuts taking the lead. This makes Coconut oil a perfect base for every cannabis-edible.

Here's what you will need for the recipe:

  • Cannabis trim (amount depends on your desired potency)
  • Coconut Oil
  • Water
  • Mason jar
  • Baking Sheet
  • Aluminum foil
  • Grinder
  • Pot (For Cooking)
  • Cheesecloth
  • Spoon

Step 1: Decarboxylate your trim.

Step 2: Fill your mason jar with coconut oil

Step 3: Fill your pot with water, and keep it over the stove with enough heat that it is not boiling yet.

Step 4: Place the decarboxylated trim and place it into the coconut oil in the mason jar, and seal the lid of the jar tightly.

Step 5: Place the mason jar in the pot and start boiling the water. Keep the temperature remains between 160℉ and below 200℉.

Step 6: Maintain the process for around 4 hours.

Step 7: After 4 hours, strain the coconut oil into a container. Now your coconut oil is ready to be used!

In the end, your cannabis-infused coconut oil should look somewhat similar to this;

Cannabis Infused Coconut Oil

What can you make with cannabis-infused coconut oil?

  • Cookies
  • Cauliflower rice
  • Coconut oil chews/macaroons
  • Banana bread
  • Banana and coconut oil smoothie

It’s clear that neglecting cannabis trim is a massive mistake, and one commonly made. Cannabis trim is the best way to make edibles, and as you can see - the potential is endless. Cannabidiol (CBD) sugar trim available at BlackTieCBD.Net. Search “Flower”, then select “Trim/Shake” within the Quantity filter on the left hand side of the screen. If you would like assistance, please feel free to call us at (888)702-2285. Speak with you soon!

December 13, 2021
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A Guide to Understanding Trichomes

If you’re a cannabis user, you’re probably familiar with the sugary, crystal-like appearance that appears on the flower, leaves, or bract - known as trichomes. Trichomes are produced across the cannabis plant, which holds the plant's cannabinoids and terpenes. Most people recognize trichomes as the ‘tiny hairs’ on the plant, so it’s likely that you’ve already seen them.

So, what are trichomes?

The word trichome originates from the Greek word “Tríchōma,” which means growth of hair. The actual definition is “appendages on plants, algae, lichens, and certain protists.” - These tiny outgrowths, or sources of resin, allow the production of cannabis concentrates like; shatter, cannabis oil, hash, and wax. Each trichome has a unique size, shape, and biochemical function.

Trichomes are minuscule biological cannabinoid factories found predominantly on the flowers and sugar leaves of weed, providing a variety of functions and benefits to the plant. Scientists have said that trichomes could affect leaf temperature and photosynthesis, or more complicated functions, such as pest-deterrence via their physical structures or production of compounds, as studied by George J Wagner, stating that trichomes;

“Guide the path of pollinators or affect photosynthesis, leaf temperature, or water loss through increased light reflectance as in desert species.”

What are the different trichomes?

Scientists have identified three categories of trichomes found on cannabis plants:

  1. Bulbous trichomes
  2. Capitate-stalked trichomes
  3. Capitate sessile trichomes

It is believed that trichomes function as a form of survival for the cannabis plant. The sticky resin that coats the plant provides a frontline defense against fungus, insects, and herbivores. Trichomes also play an essential role in helping cannabis grow in difficult climatic conditions.

  1. Bulbous trichomes
  2. These are the smallest type of trichomes, sometimes being as little as 10 microns wide - which is actually a fraction of the largest size. These can be found across the surface of the plant - but are too difficult to see.

2. Capitate sessile trichomes

These trichomes are larger than bulbous trichomes, with enough cell    numbers to form a trichome head and a very short base. These trichomes have a width of around 20-30 microns, which are not as large as the final category of trichomes, nor as easy to see.

3. Capitate-stalked trichomes

These are much larger and can be seen by the naked eye. These range from 50-100 micrometers wide typically. Capitate stalked trichomes have a stalk that is made from cells known as epidermal and hypodermic cells. On top of the stalk is the head of the resin gland, the ‘capitate.’ The ball-shaped head of the resin gland has a waxy outer cuticle layer which acts as a ‘skin.’ Inside the resin head are the cannabinoids and terpenes. These are produced by specialized cells in-between the top of the trichome stalk and the spherical resin head.

Cannabis trichomes typically appear early in the flowering stage on healthy plants. As trichome heads age, they go from being completely clear to opaque, milky white, and, eventually, amber. See below for reference;

Different Trichomes

What do the different trichome colors mean?

Clear Trichomes:

As a plant transitions into the flowering phase, noticeably the first trichomes appear. Young and immature trichomes feature a clear, translucent appearance. They maintain this appearance for the first part of this phase before their chemical composition changes significantly for the first time. This color indicates that THC and terpene production is at their peak, while CBD levels are still low. This means harvesting at this color will have a more cerebral psychoactive effect. However, it is still not ideal to harvest at this stage and should be harvested at the next.

Cloudy Trichomes:

Cloudy trichomes occur prior to harvest and indicate that cannabinoid levels have reached their maximum. This does not necessarily mean that it is an extremely potent THC strain, however, as that depends on other factors. While it doesn’t guarantee potency, it is a good indicator of when the strain has reached its production peak.

This is when most growers harvest their flowers, and it is generally considered the right time to harvest. You can also use the pistils as an indicator when more than 50% of the hairs have turned orange it means you’re at this stage.

Trichomes remain cloudy for approximately two weeks. Towards the end of this stage, they start to change appearance once again, indicating more developments in their phytochemical composition - which is why they start turning amber in color.

Amber Trichomes:

If trichomes have turned a visible amber hue, the cannabis plant has probably aged past peak potency. This trait makes trichomes a good indicator of when a plant is ready for harvest. Most growers pay close attention to the state of the plant's trichomes and try to harvest buds right when the trichomes are milky white before they have degraded to amber.

Trichomes turning amber indicate deteriorating THC levels, so it is a fine balance of checking on them several times a day to ensure that harvest happens at the peak moment for both high THC levels and the desired couchlock effects.

What impacts trichome production?

  1. Stress training
  2. Stress training can significantly increase yields when performed correctly. Higher yields tend to mean more trichomes. The process typically involves manipulating the plant's shape to distribute hormones more evenly across the top buds, allowing the plant to make better use of the light.

    However, the process of stress training can have negative consequences, like bud discoloration, re-vegging, or hermies, so it’s an ambiguous process to say the least. However, it is usually safe as long as you save any major stress for the last week or two before harvest.
  1. Lighting
  2. The light spectrum is one of the most fundamental parts of a cannabis plant’s ability to increase trichome production. The trichomes protect the plant from UV rays, which means that the more light the plant gets - the more resin it will produce.

    Some believe that exposing cannabis buds to UV-B light for the last 2-3 weeks before harvest can increase trichome production and overall potency. The most common source of UV-B light is Metal Halide grow lights.  
  1. Temperature and humidity
  2. Temperature and humidity have a massive effect on the growth of cannabis flowers. When temperature and humidity are adjusted to induce stress, the plant may increase trichome production as a defense mechanism.
  1. Adjusting the environment
  2. Each stage of cannabis plant growth influences the production of trichomes. The glands are highly fragile and volatile, which is why ensuring that the plant is growing in the right environment should be a priority - especially in the flowering stage. The purpose of adjusting heat periodically is to avoid the trichomes and terpenes from getting damaged by heat.

    This is the general rule of thumb when altering the environment:
    Humidity below 30% – Drop the humidity of the growth space below 30% RH for the last 2-3 weeks before harvest to increase trichome production.

Temperature between 70-80°F – Make sure your temperature stays under 80°F (26°C) to ensure the potency is not being baked right off your buds.

  1. Supplements
  2. It is essential to give your plants plenty of phosphorus and potassium during their flowering stage. Boosting trichome production requires that a cannabis plant is fed the correct amount of nutrients. If a plant is deficient in nutrients, it slows down all its functions.

Genetics plays the most significant role when it comes to getting the most trichomes out of your cannabis. Genetics are crucial If you want to achieve the best and most trichomes you can, so choosing genetics that produce an abundance of trichomes is essential.

December 1, 2021
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